EM algorithm is one of the core algorithms in statistics and machine learning. It has been widely used in many tools in the fields of bioinformatics, for example, motif discovery (MEME), comparative genomics (Phylo-HMM), multiple sequence alignment (ClustalW), NGS analysis (Cufflinks, RSEM, and eXpress), etc.  So, please join us to master the hardcore technique.

Dr. Kazuki Yoshida will review the following Nature Biotechnology prime article:

https://www.nature.com/articles/nbt1406